PT-141 is a synthetic peptide analogue frequently utilized in laboratory settings to investigate the activation of central melanocortin pathways and their systemic physiological effects.

Peptide Classification and Description

PT-141 (also known as Bremelanotide) is a synthetic derivative of the naturally occurring alpha-melanocyte-stimulating hormone ($\alpha$-MSH). Unlike traditional compounds that target the vascular system, PT-141 is a non-selective melanocortin receptor agonist that operates primarily through the central nervous system. It is supplied as a high-purity lyophilized powder for in-vitro testing and laboratory experimentation.

Targets, Effects, and Explored Roles

Category	PT-141 Research Details
Primary Targets	Melanocortin receptors, particularly the MC3R and MC4R subtypes.
Potential Effects	Activation of neural pathways associated with arousal, modulation of immune responses, and skin pigmentation.
Explored Roles	Research centers on its role in treating sexual dysfunction, investigating aphrodisiac properties, and studying immune system modulation.

Core Mechanism and Function

Peptide	Mechanism of Action	Key Biological Function
PT-141	Acts as a potent melanocortin receptor agonist in the hypothalamus.	Influences physiological arousal and sexual function by bypassing the cardiovascular system to act directly on the nervous system.

Clinical Potential

While strictly intended for research use in this form, the pathways activated by PT-141 are a major focal point in several clinical investigational areas:

Sexual Medicine Research: Investigating its effectiveness in addressing female sexual interest/arousal disorder (FSIAD) and male erectile dysfunction.
Immunological Studies: Exploring the potential for melanocortin agonists to regulate systemic inflammation and immune-mediated responses.
Dermatological Biology: Studying the relationship between receptor activation and the production of protective skin pigments.

Strictly RUO: This product is for Research Use Only. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

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