Ipamorelin is a highly selective growth hormone secretagogue frequently utilized in laboratory settings to study endocrine signaling and cellular repair mechanisms.

Peptide Classification and Description

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that belongs to the growth hormone secretagogue receptor (GHSR) agonist class. It is recognized in preclinical research for its ability to mimic the action of ghrelin, specifically targeting the pituitary gland to trigger secretions without significantly impacting other hormones like cortisol, prolactin, or ACTH.

Targets, Effects, and Explored Roles

Category	Ipamorelin Research Details
Primary Targets	The pituitary gland and growth hormone secretagogue receptors (GHSR).
Potential Effects	Induction of pulsatile growth hormone release and suppression of somatostatin (a GH inhibitor).
Explored Roles	Studies focus on its role in bone mineral density, muscle tissue repair, and peptide receptor kinetics.

Core Mechanism and Function

Peptide	Mechanism of Action	Key Biological Function
Ipamorelin	Stimulates the pituitary gland and reduces somatostatin production in animal models.	Enhances the production of IGF-1 (Insulin-like Growth Factor 1) to support growth and repair of muscular and skeletal tissues.

Clinical Potential

While strictly intended for research use, Ipamorelin is a focal point in several investigational areas:

Musculoskeletal Development: Exploring the acceleration of repair in skeletal muscle and the increase of bone density.
Endocrine Biology: Researching the management of growth-related deficiencies through selective receptor activation.
Gastroenterology: Investigating potential roles in gastric motility and post-operative recovery models.

Strictly RUO: This product is for Research Use Only. It is not intended for human consumption or clinical applications.

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